Cleaved-Notch 4 (V1432) rabbit pAb
Ref. EK-ES6409
50µl
188.00€
100µl
316.00€
Product Information
Name:Cleaved-Notch 4 (V1432) rabbit pAb
Synonyms:
- NOTCH4; INT3; Neurogenic locus notch homolog protein 4; Notch 4; hNotch4
Brand:ELK Biotechnology
Description:notch 4(NOTCH4) Homo sapiens This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor may play a role in vascular, renal and hepatic development. Mutations in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants, at least one of which
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Chemical properties
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