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Pim-1 rabbit pAb

Ref. EK-ES6589

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ELK Biotechnology

Product Information

Name:Pim-1 rabbit pAb
Synonyms:
  • PIM1; Serine/threonine-protein kinase pim-1
Brand:ELK Biotechnology
Description:The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011],
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Chemical properties

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