Arkadia rabbit pAb
Ref. EK-ES6675
Product Information
Name:Arkadia rabbit pAb
Synonyms:
- RNF111; E3 ubiquitin-protein ligase Arkadia; RING finger protein 111
Brand:ELK Biotechnology
Description:ring finger protein 111(RNF111) Homo sapiens The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012],
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Chemical properties
Technical inquiry about: Arkadia rabbit pAb
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