TDG rabbit pAb
Ref. EK-ES7359
50µl
188.00€
100µl
316.00€
Product Information
Name:TDG rabbit pAb
Synonyms:
- TDG; G/T mismatch-specific thymine DNA glycosylase; Thymine-DNA glycosylase
Brand:ELK Biotechnology
Description:The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008],
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Chemical properties
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