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Cyclin D3 (phospho Thr283) rabbit pAb

Ref. EK-ES7914

50µl
188.00 €
100µl
316.00 €
Estimated delivery in United States, on Tuesday 15 Oct 2024

Product Information

Name:
Cyclin D3 (phospho Thr283) rabbit pAb
Synonyms:
  • CCND3; G1/S-specific cyclin-D3
Description:

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008],

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
ELK Biotechnology
Long term storage:
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Chemical properties

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Hazard Info

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EQ:
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Forbidden to fly:
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