N-CoR rabbit pAb
Ref. EK-ES8074
| 50µl | 188.00 € | ||
| 100µl | 316.00 € |
Product Information
- NCOR1; KIAA1047; Nuclear receptor corepressor 1; N-CoR; N-CoR1
This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.[provided by RefSeq, Jun 2010],
Chemical properties
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