Perforin 1 rabbit pAb
Ref. EK-ES8510
Product Information
Name:Perforin 1 rabbit pAb
Synonyms:
- Perforin-1 (P1) (Cytolysin) (Lymphocyte pore-forming protein) (PFP)
Brand:ELK Biotechnology
Description:The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008],
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Chemical properties
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