Perforin 1 rabbit pAb
Ref. EK-ES8510
50µl | 188.00 € | ||
100µl | 316.00 € |
Product Information
- Perforin-1 (P1) (Cytolysin) (Lymphocyte pore-forming protein) (PFP)
The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008],
Chemical properties
Technical inquiry about: EK-ES8510 Perforin 1 rabbit pAb
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