Flk-1/VEGFR2 rabbit pAb
Ref. EK-ES8590
| 50µl | 188.00 € | ||
| 100µl | 316.00 € |
Product Information
- Vascular endothelial growth factor receptor 2 (VEGFR-2;EC 2.7.10.1;Fetal liver kinase 1;FLK-1;Kinase insert domain receptor;KDR;Protein-tyrosine kinase receptor flk-1;CD antigen CD309)
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009],
Chemical properties
Technical inquiry about: EK-ES8590 Flk-1/VEGFR2 rabbit pAb
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