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CD152 rabbit pAb

Ref. EK-ES8684

50µl
188.00€
100µl
316.00€
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ELK Biotechnology

Product Information

Name:CD152 rabbit pAb
Synonyms:
  • Cytotoxic T-lymphocyte protein 4 (Cytotoxic T-lymphocyte-associated antigen 4;CTLA-4;CD antigen CD152)
Brand:ELK Biotechnology
Description:This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008],
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Chemical properties

Technical inquiry about: CD152 rabbit pAb

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