

Thyroglobulin rabbit pAb
Ref. EK-ES8743
50µl
188.00€
100µl
316.00€


Product Information
Name:Thyroglobulin rabbit pAb
Synonyms:
- Thyroglobulin (Tg)
Brand:ELK Biotechnology
Description:Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009],
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Chemical properties
Technical inquiry about: Thyroglobulin rabbit pAb
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