Insulin rabbit pAb
Ref. EK-ES8775
50µl | 188.00 € | ||
100µl | 316.00 € |
Product Information
- Insulin [Cleaved into: Insulin B chain; Insulin A chain]
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010],
Chemical properties
Technical inquiry about: EK-ES8775 Insulin rabbit pAb
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