IBTK rabbit pAb
Ref. EK-ES9099
50µl | 188.00 € | ||
100µl | 316.00 € |
Product Information
Bruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils. The protein encoded by this gene binds to BTK and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014],
Chemical properties
Technical inquiry about: EK-ES9099 IBTK rabbit pAb
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