HECW1 rabbit pAb
Ref. EK-ES9625
50µl
188.00€
100µl
316.00€
Product Information
Name:HECW1 rabbit pAb
Brand:ELK Biotechnology
Description:function:E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 C2 domain.,similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.,similarity:Contains 2 WW domains.,subunit:Interacts with DVL1 and SSR3. Also interacts with mutant SOD1.,tissue specificity:Predominantly expressed in neurons of adult and fetal brain. Weakly expressed in the kidney.,
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Technical inquiry about: HECW1 rabbit pAb
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