GCH1 rabbit pAb
Ref. EK-ES9684
50µl
188.00€
100µl
316.00€
Product Information
Name:GCH1 rabbit pAb
Brand:ELK Biotechnology
Description:This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme. [provided by RefSeq, Jul 2008],
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Chemical properties
Technical inquiry about: GCH1 rabbit pAb
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