Busulfan

CAS: 55-98-1

Ref. TM-T0923

Product Information

• Name: Busulfan
• Synonyms: Myleran, Sulphabutin, Busulphan, 1,4-Bis(methanesulfonoxy)butane, 1,4-Bis(methanesulfonyloxy)butane, 1,4-Butanediol dimesylate, 1,4-Butanediol dimethanesulfonate, 1,4-Butanediol, 1,4-dimethanesulfonate, 1,4-Dibutanediol dimethanesulfonate, 1,4-Dimethanesulfonoxybutane, 1,4-Dimethylsulfonyloxybutane, 2041Cb, 4-Methylsulfonyloxybutyl methanesulfonate, An 33501, Busilvex, Busulfano, Busulfex, Busulphan, Butane-1,4-diyl bis(methanesulfonate), Butanediol dimethanesulphonate (mylran), 1,4-, Cb 2041, Citosulfan, Glyzophrol, Gt 2041, Gt 41, Leucosulfan, Mablin, Methanesulfonic acid, tetramethylene ester, Mielevcin, Mielosan, Mielucin, Milecitan, Mileran, Misulban, Mitostan, Myeloleukon, Myelosan, Mylecytan, Myleran, Myran, Nci C01592, Nsc 750, Sulfabutin, Sulphabutin, Tetramethylene bis(methanesulfonate), X 149
• CAS: 55-98-1

Description

Busulfan (Busulphan) is a synthetic derivative of dimethane-sulfonate with antineoplastic and cytotoxic properties. Although its mechanism of action is not fully understood, busulfan appears to act through the alkylation of DNA. Following systemic absorption of busulfan, carbonium ions are formed, resulting in DNA alkylation and DNA breaks and inhibition of DNA replication and RNA transcription.

• Brand: Targetmol

Chemical properties

• Molecular weight: 246.3
• Formula: C₆H₁₄O₆S₂
• Purity: 99.77%
• Color/Form: White Needles Physical Description White Crystals Or Powder (Ntp 1992)