Estimated delivery in United States, on Friday 9 Aug 2024
Product Information
Name:
AZ12601011
Synonyms:
- AZ-12601011
CAS:
Description:
AZ12601011 is a highly potent and selective inhibitor of the TGFBR1 kinase, administered orally. It displays an IC50 of 18 nM and a Kd of 2.9 nM. By selectively targeting ALK4, TGFBR1, and ALK7, AZ12601011 effectively inhibits the phosphorylation of SMAD2. Additionally, it has been shown to hinder the growth and metastasis of mammary tumors [1].
Brand:
Targetmol
Long term storage:
Notes:
Chemical properties
Molecular weight:
313.36
Formula:
C19H15N5
Purity:
98%
Color/Form:
Solid
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TM-T10426 AZ12601011
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