ERRα antagonist-1
CAS: 1072145-33-5
Ref. TM-T11230
| 5mg | 73.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 231.00 € | ||
| 50mg | 347.00 € | ||
| 100mg | 510.00 € | ||
| 1ml*10 (DMSO) | 81.00 € |
Product Information
- ERR+/- antagonist-1, ERRa antagonist-1
ERRα antagonist-1 (ERR+/- antagonist-1) is a high-affinity, selective antagonist of the estrogen-related receptor α (ERRα). It effectively prevents the interaction of ERRα with both Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β, displaying IC50 values of 170 nM and 180 nM, respectively. Notably, ERRα antagonist-1 does not interfere with the interactions involving ERRβ or ERRγ and the PGC-1α and PGC-1β coactivators. Furthermore, it does not affect the interaction between either ERα or ERβ and PGC-1α or SRC-1.
Chemical properties
Technical inquiry about: TM-T11230 ERRα antagonist-1
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