Pimethixene

CAS: 314-03-4

Ref. TM-T12489

Product Information

• Name: Pimethixene
• Synonyms: Calmixen, Pimetixene, 1-Methyl-4-(thioxanthen-9-ylidene)piperidine, 1-Methyl-4-thioxanthen-9-ylidenepiperidine, 1-methyl-4-(9H-thioxanthen-9-ylidene)piperidine, 9-(1-Methyl-4-piperidinylidene)thioxanthene, 9-(1-Methyl-4-piperidylidene)thioxanthene, 9-(N-Methyl-4′-piperidylene)thioxanthene, 9-(N-Methyl-4′-piperidylidene)-thioxanthene, Bp 400, Bp 400S, Brn 4143937, Calmixen, Calmixene, Cga 123427, Mepithiathene, Pimethixene [INN], Pimethixenum, Pimethixenum [INN-Latin], Pimetixene, Pimetixeno, Pimetixeno [INN-Spanish], Piperidine, 1-methyl-4-(9H-thioxanthen-9-ylidene)-, Piperidine, 1-methyl-4-(9H-thioxanthen-9-ylidene)- (9CI), Piperidine, 1-methyl-4-thioxanthen-9-ylidene-, Unii-T46J20J26F
• CAS: 314-03-4

Description

Pimethixene (Calmixen) is a highly potent 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2 receptors antagonist(pKis of 7.63, 10.22, 10.44, 8.42, 10.14, 8.19, 7.54, 8.61 and 9.38, respectively).

• Brand: Targetmol

Chemical properties

• Molecular weight: 293.43
• Formula: C₁₉H₁₉NS
• Purity: 99.1%
• Color/Form: Solid
• InChI: InChI=1S/C19H19NS/c1-20-12-10-14(11-13-20)19-15-6-2-4-8-17(15)21-18-9-5-3-7-16(18)19/h2-9H,10-13H2,1H3
• InChI key: InChIKey=NZLVRVYNQYGMAB-UHFFFAOYSA-N
• SMILES: CN1CCC(=C2c3ccccc3Sc3ccccc32)CC1