PXS-5153A monohydrochloride
CAS: 2125956-82-1
Ref. TM-T12585L
25mg | 916.00 € | ||
50mg | 1,271.00 € | ||
100mg | 1,739.00 € |
Product Information
- PXS-5153A monohydrochloride (2125956-82-1 free base)
PXS-5153A monohydrochloride is a potent, selective, orally active and fast-acting lysyl oxidase like 2/3 enzymatic (LOXL2/LOXL3) inhibitor, with an IC 50 of <40 nM for LOXL2 across all mammalian species and an IC 50 of 63 nM for human LOXL3. PXS-5153A monohydrochloride dose-dependently reduced LOXL2-mediated collagen oxidation and collagen crosslinking in vitro which may represent an innovative therapeutic approach for the treatment of fibrosis
Chemical properties
Technical inquiry about: TM-T12585L PXS-5153A monohydrochloride
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