SB-657510
CAS: 474960-44-6
Ref. TM-T12848
1mg | 122.00 € | ||
5mg | 352.00 € | ||
10mg | 527.00 € | ||
25mg | 852.00 € | ||
50mg | 1,143.00 € | ||
100mg | 1,566.00 € | ||
500mg | 3,132.00 € | ||
1ml*10 (DMSO) | 393.00 € |
Product Information
SB-657510 is a urotensin II (UII) receptor (UT) antagonist. The Ki values of UT for human, monkey, cat, rat and mouse were 61, 17, 30, 65 and 56 nM, respectively. SB-657510 plays an anti-inflammatory role by inhibiting UII-induced inflammatory mediators, such as adhesion molecules, in human vascular endothelial cells and upregulation of cytokines and tissue factors. SB 657510 has a therapeutic effect on diabetes-related atherosclerotic disease in diabetic mouse models.
Chemical properties
Technical inquiry about: TM-T12848 SB-657510
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