Estimated delivery in United States, on Thursday 27 Jun 2024
Product Information
Name:
Sitravatinib malate
Synonyms:
- MGCD516 malate, MG-516 malate
CAS:
Description:
Sitravatinib malate is an orally bioavailable receptor inhibitor of tyrosine kinase (RTK) (IC50s of 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0.5 nM, 29 nM, 5 nM, and 9 nM for Axl, MER, VEGFR3, VEGFR2, VEGFR1, KIT, FLT3, DDR2, DDR1, TRKA, TRKB, respectively.) , shows potent single-agent antitumor efficacy and enhances the activity of PD-1 blockade through promoting an antitumor immune microenvironment.
Brand:
Targetmol
Long term storage:
Notes:
Chemical properties
Molecular weight:
763.76
Formula:
C37H35F2N5O9S
Purity:
98%
Color/Form:
Solid
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TM-T12925 Sitravatinib malate
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