TAM Receptor
TAM receptor inhibitors target the TAM family of receptor tyrosine kinases, which includes Tyro3, Axl, and Mer. These receptors are involved in the regulation of immune responses, cell survival, and clearance of apoptotic cells. Dysregulation of TAM receptors is implicated in cancer, autoimmune diseases, and chronic inflammation. At CymitQuimica, we offer TAM receptor inhibitors to aid your research in immunology, oncology, and inflammation.
Found 30 products for "TAM Receptor".
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TAM-IN-2
CAS:TAM-IN-2 is an inhibitor of TAM.Formula:C31H27F2N7O3Purity:98.09% - 99.74%Color and Shape:SolidMolecular weight:583.59XL092
CAS:XL092 (JUN04542) is an Axl Mer cMet KDR inhibitor for the treatment of Axl and Mer receptor tyrosine kinase- dependent disorders.Formula:C29H25FN4O5Purity:98.60%Color and Shape:SolidMolecular weight:528.53UNC2881
CAS:UNC2881 is a specific Mer tyrosine kinase inhibitor (IC50: 4.3 nM). It is about 83- and 58-fold higher selectivity than Axl and Tyro3, respectively.Formula:C25H33N7O2Purity:98.97% - 99.85%Color and Shape:SolidMolecular weight:463.58SGI-7079
CAS:SGI-7079: selective Axl inhibitor; hinders tumor growth dose-dependently; may target EGFR inhibitor resistance.Formula:C26H26FN7Purity:95.51% - 99.26%Color and Shape:SolidMolecular weight:455.53Ref: TM-T6982
2mg39.00€5mg58.00€1mL*10mM (DMSO)64.00€10mg92.00€25mg178.00€50mg230.00€100mg334.00€500mg782.00€LDC1267
CAS:LDC1267 is a excellently specific TAM(Tyro3, Axl and Mer) kinase inhibitor, for Mer( IC50<5 nM), Tyro3(IC50=8 nM), and Axl(IC50=29 nM).Formula:C30H26F2N4O5Purity:99.38% - 99.88%Color and Shape:SolidMolecular weight:560.55NPS-1034
CAS:NPS-1034 is a dual Met/Axl inhibitor with IC50 of 48 nM and 10.3 nM, respectively.Formula:C31H23F2N5O3Purity:98.48%Color and Shape:SolidMolecular weight:551.54UNC2541
CAS:UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor.Formula:C24H34FN7O2Purity:98.33%Color and Shape:White SolidMolecular weight:471.572-D08
CAS:2-D08 is a synthetic flavone that inhibits sumoylation, also inhibits Axl with an IC50 of 0.49 nM.2-D08 showed anti-aggregatory and neuroprotective effect.Formula:C15H10O5Purity:98.58% - 99.45%Color and Shape:Yellow SolidMolecular weight:270.24Ref: TM-T7379
2mg39.00€5mg54.00€1mL*10mM (DMSO)59.00€10mg93.00€25mg170.00€50mg268.00€100mg447.00€200mg650.00€Bemcentinib
CAS:Bemcentinib (R428) is a selective inhibitor of Axl (IC50: 14 nM) and has been investigated for the treatment of NSCLC.Formula:C30H34N8Purity:97% - 99.8%Color and Shape:SolidMolecular weight:506.64Ref: TM-T6269
1mg38.00€2mg50.00€5mg82.00€1mL*10mM (DMSO)96.00€10mg137.00€25mg202.00€50mg259.00€100mg442.00€200mg588.00€500mg898.00€RU-301
CAS:RU-301 is a novel pan-tam inhibitorFormula:C21H19F3N4O4SPurity:98.87%Color and Shape:SolidMolecular weight:480.46Ref: TM-T7425
1mg98.00€5mg222.00€1mL*10mM (DMSO)241.00€10mg344.00€25mg587.00€50mg803.00€100mg1,063.00€UNC569
CAS:UNC569 selectively inhibits kidney URAT1, regulating uric acid excretion and aiding gout patient's uric balance.Formula:C22H29FN6Purity:98.91% - 99.67%Color and Shape:SolidMolecular weight:396.5BMS 777607
CAS:BMS 777607 (BMS 817378) is a Met-related inhibitor for c-Met/Axl/Ron/Tyro3. BMS-777607 has been investigated for the basic science of Malignant Solid Tumour.Formula:C25H19ClF2N4O4Purity:98.89% - >99.99%Color and Shape:SolidMolecular weight:512.89Ref: TM-T2699
1mg34.00€5mg74.00€1mL*10mM (DMSO)87.00€10mg117.00€25mg207.00€50mg340.00€100mg505.00€500mg1,108.00€UNC2250
CAS:UNC2250 is an effective and specific Mer inhibitor (IC50=1.7 nM).Formula:C24H36N6O2Purity:98.57% - 99.87%Color and Shape:SolidMolecular weight:440.58Gilteritinib
CAS:Gilteritinib (ASP2215) is a potent inhibitor at the FMS-related tyrosine kinase 3 (FLT3) and AXL tyrosine kinase receptors (IC50 = 0.29 nM and <1 nM,Formula:C29H44N8O3Purity:97.75% - 99.90%Color and Shape:SolidMolecular weight:552.71Ref: TM-T4409
1mg38.00€2mg52.00€5mg85.00€10mg114.00€25mg177.00€50mg261.00€100mg411.00€500mg954.00€1g1,288.00€Ningetinib
CAS:Ningetinib (CT-053) (CT053PTSA) is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.Formula:C31H29FN4O5Purity:99.95% - 99.98%Color and Shape:SolidMolecular weight:556.58ONO-7475
CAS:ONO-7475 is an inhibitor with high specificity for anexelekto and MER tyrosine kinaseFormula:C32H26N4O6Purity:98.74%Color and Shape:White SolidMolecular weight:562.57Cabozantinib hydrochloride
CAS:Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6Formula:C28H25ClFN3O5Purity:99.97%Color and Shape:White SolidMolecular weight:537.96Ref: TM-T5164
1mg42.00€2mg52.00€5mg65.00€10mg92.00€25mg160.00€50mg235.00€100mg330.00€200mg538.00€500mg860.00€CEP-40783
CAS:CEP-40783 (RXDX-106) is an effective, specific and orally active AXL/c-Met inhibitor (IC50: 7/12 nM). It also inhibits MER and TYRO3 (IC50: 29/19 nM).Formula:C31H26F2N4O6Purity:99.76% - 99.84%Color and Shape:White SolidMolecular weight:588.56Ningetinib Tosylate
CAS:Ningetinib Tosylate is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.Formula:C38H37FN4O8SPurity:99.93%Color and Shape:SolidMolecular weight:728.79Cabozantinib
CAS:Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM).Formula:C28H24FN3O5Purity:99.82% - 99.89%Color and Shape:SolidMolecular weight:501.51
