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Apricitabine

CAS: 160707-69-7

Ref. TM-T14313

1mg
54.00 €
5mg
90.00 €
10mg
130.00 €
25mg
209.00 €
50mg
329.00 €
100mg
543.00 €
1ml*10 (DMSO)
92.00 €
Estimated delivery in United States, on Tuesday 28 May 2024

Product Information

Name:
Apricitabine
Synonyms:
  • AVX754, SPD754
  • (-)-2′-Deoxy-3′-oxa-4′-thiocytidine
  • (-)-Bch 10652
  • 1,3-Oxathiolane, 2(1H)-pyrimidinone deriv.
  • 2(1H)-Pyrimidinone, 4-amino-1-[(2R,4R)-2-(hydroxymethyl)-1,3-oxathiolan-4-yl]-
  • 2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-4-yl]-, (2R-cis)-
  • 4-Amino-1-[(2R,4R)-2-(hydroxymethyl)-1,3-oxathiolan-4-yl]-2(1H)-pyrimidinone
  • Avx 754
  • Bch 10618
  • Spd 754
  • See more synonyms
Description:

Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 μM), the (-) enantiomer of 2′-deoxy-3′-oxy-4′-thiocytidine (dOTC) . Apricitabine inhibits DNA polymerase α, β and γ with Ki values of 300 μM, 12 μM and 112.25 μM, respectively. Apricitabine has shown good antiretroviral therapeutic efficacy in antiretroviral HIV-infected patients, with good tolerability and low selective resistance.

Brand:
Targetmol
Long term storage:
Notes:

Chemical properties

Molecular weight:
229.26
Formula:
C8H11N3O3S
Purity:
100%
Color/Form:
Solid
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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