Ritodrine hydrochloride

CAS: 23239-51-2

Ref. TM-T1433

Product Information

• Name: Ritodrine hydrochloride
• Synonyms: DU21220, Ritodrine HCl, NSC 291565, 4-(1-Hydroxy-2-{[2-(4-Hydroxyphenyl)Ethyl]Amino}Propyl)Phenol, 4-[(1R,2S)-1-hydroxy-2-{[2-(4-hydroxyphenyl)ethyl]amino}propyl]phenol hydrochloride (1:1), Benzenemethanol, 4-hydroxy-α-[(1R)-1-[[2-(4-hydroxyphenyl)ethyl]amino]ethyl]-, hydrochloride (1:1), (αS)-rel-, Benzenemethanol, 4-hydroxy-α-[(1R)-1-[[2-(4-hydroxyphenyl)ethyl]amino]ethyl]-, hydrochloride, (αS)-rel-, Benzenemethanol, 4-hydroxy-α-[1-[[2-(4-hydroxyphenyl)ethyl]amino]ethyl]-, hydrochloride, (R*,S*)-, Benzyl alcohol, p-hydroxy-α-[1-[(p-hydroxyphenethyl)amino]ethyl]-, hydrochloride, erythro-, Du 21220, Hydrogen Chloride 4-(1-Hydroxy-2-{[2-(4-Hydroxyphenyl)Ethyl]Amino}Propyl)Phenol (1:1:1), Miolene, NSC 291565, Pre-Par, Prempar, Ritodrine HCl, Utemerin, Utopar, Yutopar
• CAS: 23239-51-2

Description

Ritodrine hydrochloride (NSC 291565) binds to and activates beta-2 adrenergic receptors of myometrial cells in the uterus, which decreases the intensity and frequency of uterine contractions. Ritodrine hydrochloride (NSC 291565) is a phenethylamine derivative with tocolytic activity. Specifically, Ritodrine hydrochloride (NSC 291565) probably activates adenyl cyclase, thereby increasing production of cyclic adenosine monophosphate (cAMP), which in turn enhances the efflux of calcium from vascular smooth muscle cells. A lack of intracellular calcium prevents uterine myometrial contractions. In addition, this agent may directly inactivate myosin light chain kinase, a critical enzyme necessary for the initiation of muscle contractions.

• Brand: Targetmol

Chemical properties

• Molecular weight: 323.82
• Formula: C₁₇H₂₁NO₃·HCl
• Purity: 99.89%
• Color/Form: Solid