Lometrexol
CAS: 106400-81-1
Ref. TM-T15826
| 1mg | 95.00 € | ||
| 5mg | 219.00 € | ||
| 10mg | 319.00 € | ||
| 25mg | 540.00 € | ||
| 50mg | 773.00 € | ||
| 100mg | 1,072.00 € | ||
| 1ml*10 (DMSO) | 254.00 € |
Estimated delivery in United States, on Tuesday 21 May 2024
Product Information
Name:
Lometrexol
Synonyms:
- LY 264618, DDATHF
- Lometrexolum
- Lometrexolum [INN-Latin]
- Unii-6P3Avy8A7Q
- L-Glutamic acid, N-(4-(2-((6R)-2-amino-1,4,5,6,7,8-hexahydro-4-oxopyrido(2,3-d)pyrimidin-6-yl)ethyl)benzoyl)-
- L-Glutamic acid, N-(4-(2-(2-amino-1,4,5,6,7,8-hexahydro-4-oxopyrido(2,3-d)pyrimidin-6-yl)ethyl)benzoyl)-, (R)-
- N-(4-{2-[(6R)-2-amino-4-oxo-1,4,5,6,7,8-hexahydropyrido[2,3-d]pyrimidin-6-yl]ethyl}benzoyl)-L-glutamic acid
CAS:
Description:
Lometrexol (LY 264618), an antipurine Antifolate, can inhibit the activity of glycinamide ribonucleotide formyltransferase (GARFT) but do not induce detectable levels of DNA strand breaks. Lometrexol can further inhibit de novo purine synthesis, causing abnormal cell proliferation and Apoptosis, even cell cycle arrest. Lometrexol has anticancer activity. Lometrexol also is a potent human Serine hydroxymethyltransferase1/2 (hSHMT1/2) inhibitor.
Brand:
Targetmol
Long term storage:
Notes:
Chemical properties
Molecular weight:
443.45
Formula:
C21H25N5O6
Purity:
98.57%
Color/Form:
Solid
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
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