NS-2028
CAS: 204326-43-2
Ref. TM-T16344
| 1mg | 59.00 € | ||
| 2mg | 87.00 € | ||
| 5mg | 129.00 € | ||
| 10mg | 226.00 € | ||
| 25mg | 464.00 € | ||
| 50mg | 690.00 € | ||
| 100mg | 975.00 € | ||
| 1ml*10 (DMSO) | 143.00 € |
Product Information
- NS2028
- 1H,4H-[1,2,4]Oxadiazolo[3,4-c][1,4]benzoxazin-1-one, 8-bromo-
- 4H-8-Bromo-1,2,4-oxadiazolo(3,4-d)ben(b)(1,4)oxazin-1-one
- 8-Bromo-1H,4H-[1,2,4]oxadiazolo[3,4-c][1,4]benzoxazin-1-one
- Ns 2028
NS-2028 is a highly selective soluble Guanylyl Cyclase (sGC) inhibitor (IC50: 30 nM and 200 nM for basal and NO-stimulated enzyme activity). It is commonly used in the research of nitric oxide signaling pathways. NS-2028 inhibits soluble Guanylyl Cyclase activity in homogenates of mouse cerebellum and neuronal NO synthase (IC50: 17 nM and 20 nM). NS-2028 inhibits 3-morpholino-sydnonimine (SIN-1)-elicited formation of cyclic GMP in human cultured umbilical vein endothelial cells (IC50: 30 nM). NS-2028 inhibits NO-dependent relaxant responses in non-vascular smooth muscle completely (1 μM). NS-2028 decreases vascular endothelial growth factor-induced angiogenesis and permeability.
Chemical properties
Technical inquiry about: TM-T16344 NS-2028
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