NS13001
CAS: 1063331-94-1
Ref. TM-T16345
1mg | 54.00 € | ||
5mg | 135.00 € | ||
10mg | 226.00 € | ||
25mg | 369.00 € | ||
50mg | 546.00 € | ||
100mg | 794.00 € | ||
1ml*10 (DMSO) | 94.00 € |
Product Information
- N-(4-chlorophenyl)-2-(3,5-dimethylpyrazol-1-yl)-9-methylpurin-6-amine, N-(4-Chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-9-methyl-9H-purin-6-amine
NS13001 (N-(4-Chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-9-methyl-9H-purin-6-amine) is a potent, selective, orally active allosteric positive modulator of SK channels (small conductance calcium-activated potassium channels). The EC50s are 1.8 and 0.14 μM for SK2 and SK3, respectively. NS13001 holds promise as a potential therapeutic agent for treatment of spinocerebellar ataxia type 2 (SCA2) and possibly other cerebellar ataxias.
Chemical properties
Technical inquiry about: TM-T16345 NS13001
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