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PF-04995274
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PF-04995274

CAS: 1331782-27-4

Ref. TM-T16481

1mg
35.00 €
5mg
73.00 €
10mg
121.00 €
25mg
193.00 €
50mg
345.00 €
100mg
495.00 €
1ml*10 (DMSO)
73.00 €
Estimated delivery in United States, on Thursday 9 May 2024

Product Information

Name:
PF-04995274
Synonyms:
  • PF04995274
Description:

PF-04995274 is an effective, high-affinity, and partial serotonin 4 receptor (5-HT4R) agonist. PF-04995274 is brain penetrant and can be used for cognitive disorders associated with Alzheimer's disease. PF-04995274 has an EC50 range of 0.26-0.47 nM for human 5-HT4A/4B/4D/4E (Ki range of 0.15-0.46 nM). It also has an EC50 range of 0.59-0.65 nM for rat 5-HT4S/4L/4E (Ki of 0.30 nM for rat 5-HT4S).

Brand:
Targetmol
Long term storage:
Notes:

Chemical properties

Molecular weight:
432.51
Formula:
C23H32N2O6
Purity:
99.55%
Color/Form:
Solid
InChI:
InChI=1S/C23H32N2O6/c26-23(7-12-27-13-8-23)16-25-9-4-17(5-10-25)14-29-22-21-19(30-18-6-11-28-15-18)2-1-3-20(21)31-24-22/h1-3,17-18,26H,4-16H2/t18-/m1/s1
InChI key:
InChIKey=WLLOFQROROXOMO-GOSISDBHSA-N
SMILES:
OC1(CN2CCC(COc3noc4cccc(O[C@@H]5CCOC5)c34)CC2)CCOCC1
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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