Estimated delivery in United States, on Thursday 16 May 2024
Product Information
Name:
Pyr10
Synonyms:
- Pyr-10
CAS:
Description:
Pyr10 is a pyrazole derivative and a selective TRP cation 3 inhibitor. Pyr10 has the ability to distinguish between receptor-operated TRPC3 and native stromal interaction molecule 1 (STIM1)/Orai1 channels. Pyr10 inhibits Ca2+ influx in carbachol-stimulated TRPC3-transfected HEK293 cells (IC50: 0.72 μM) (IC50 of 13.08 μM for store-operated Ca2+ entry in BRL-2H3 cells) .
Brand:
Targetmol
Long term storage:
Notes:
Chemical properties
Molecular weight:
449.37
Formula:
C18H13F6N3O2S
Purity:
99.7%
Color/Form:
Solid
InChI:
InChI=1S/C18H13F6N3O2S/c1-11-2-8-14(9-3-11)30(28,29)26-12-4-6-13(7-5-12)27-16(18(22,23)24)10-15(25-27)17(19,20)21/h2-10,26H,1H3
InChI key:
InChIKey=CVALMMCIOLXHDM-UHFFFAOYSA-N
SMILES:
Cc1ccc(S(=O)(=O)Nc2ccc(-n3nc(C(F)(F)F)cc3C(F)(F)F)cc2)cc1
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TM-T16686 Pyr10
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