TRP/TRPV Channel
TRP (Transient Receptor Potential) channels, including the TRPV subfamily, are a group of ion channels involved in various sensory processes, such as temperature sensation, pain perception, and osmoregulation. TRP channels are widely expressed in different tissues and play a role in physiological responses to environmental stimuli. The TRPV channels, in particular, are involved in detecting temperature changes and are implicated in conditions such as chronic pain, inflammation, and cancer. At CymitQuimica, we offer a comprehensive range of TRP/TRPV channel modulators to support your research in sensory biology, pain management, and signal transduction.
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GFB-8438
CAS:2304549-73-1
GFB-8438 is a potent and subtype selective inhibitor of TRPC5(IC50s of 0.18 and 0.29 μM …
Formula:
C16H14ClF3N4O2
Purity:
99.58%
Color and Shape:
Solid
Molecular weight:
386.76
Ref: TM-T11394
| 2mg | 35.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 114.00 € | ||
| 50mg | 171.00 € | ||
| 100mg | 243.00 € | ||
| 200mg | 359.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
IA-Alkyne
CAS:930800-38-7
IA-Alkyne: TRPC agonist, cysteine-reactivity probe, potential in respiratory infection study.
Formula:
C8H12INO
Purity:
≥98%
Color and Shape:
Solid
Molecular weight:
265.09
Ref: TM-T15543
| 1mg | 59.00 € | ||
| 5mg | 123.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 257.00 € | ||
| 50mg | 322.00 € | ||
| 100mg | 444.00 € | ||
| 1mL*10mM (DMSO) | 121.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
(Z)-Capsaicin
CAS:25775-90-0
(Z)-Capsaicin (Zucapsaicin) is a medication used to treat osteoarthritis of the knee and Others neuropathic …
Formula:
C18H27NO3
Purity:
99.39% - 99.67%
Color and Shape:
Solid
Molecular weight:
305.41
Ref: TM-T1109
| 10mg | 52.00 € | ||
| 50mg | 152.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
BI-749327
CAS:2361241-23-6
BI-749327 is a high selectivity and orally bioavailable antagonist of TRPC6 (IC50s: 13 nM, 19 …
Formula:
C23H21F3N4O2
Purity:
99.68%
Color and Shape:
Solid
Molecular weight:
442.43
Ref: TM-T10537
| 1mg | 130.00 € | ||
| 2mg | 177.00 € | ||
| 5mg | 270.00 € | ||
| 10mg | 425.00 € | ||
| 25mg | 626.00 € | ||
| 50mg | 819.00 € | ||
| 100mg | 1,094.00 € | ||
| 500mg | 2,188.00 € | ||
| 1mL*10mM (DMSO) | 300.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
TRPV4 agonist-1 free base
CAS:2314467-59-7
TRPV4 agonist-1 free base (OUN67600) is an agonist of transient receptor potential vanilloid 4 (TRPV4;EC50 …
Formula:
C25H22F2N4O2
Purity:
99.86%
Color and Shape:
Solid
Molecular weight:
448.46
Ref: TM-T13214L
| 2mg | 41.00 € | ||
| 5mg | 63.00 € | ||
| 10mg | 89.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 273.00 € | ||
| 100mg | 378.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Oleoyl Serotonin
CAS:1002100-44-8
Oleoyl Serotonin is an antagonist of hTRPV1 with an IC50 of 2.57 μM.
Formula:
C28H44N2O2
Purity:
100.00%
Color and Shape:
Solid
Molecular weight:
440.66
Ref: TM-T22124
| 5mg | 64.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 181.00 € | ||
| 50mg | 309.00 € | ||
| 100mg | 536.00 € | ||
| 500mg | 1,170.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
NGD-8243
CAS:573678-04-3
NGD-8243 (N-[4-(trifluoromethyl)phenyl]-7-[3-(trifluoromethyl)pyridin-2-yl]quinazolin-4-amine) is a TRPV1 inhibitor and can be used in studies for prevention
Formula:
C21H12F6N4
Purity:
90%
Color and Shape:
Solid
Molecular weight:
434.34
Ref: TM-T9818
| 1mg | 183.00 € | ||
| 5mg | 406.00 € | ||
| 10mg | 602.00 € | ||
| 25mg | 922.00 € | ||
| 50mg | 1,286.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
TRPA1-IN-2
CAS:2415206-22-1
TRPA1-IN-2 is a potent and orally active TRPA1 inhibitor with an IC50 value of 0.04 …
Formula:
C24H25F3N4O
Purity:
98.05%
Color and Shape:
Soild
Molecular weight:
442.48
Ref: TM-T77511
| 1mg | 124.00 € | ||
| 5mg | 305.00 € | ||
| 10mg | 461.00 € | ||
| 25mg | 784.00 € | ||
| 50mg | 1,095.00 € | ||
| 100mg | 1,475.00 € | ||
| 1mL*10mM (DMSO) | 337.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
AP 18
CAS:55224-94-7
AP-18 is a potent and selective TRPA1 inhibitor.
Formula:
C11H12ClNO
Purity:
90% - 99.85%
Color and Shape:
Solid
Molecular weight:
209.67
Ref: TM-T21543
| 2mg | 35.00 € | ||
| 5mg | 50.00 € | ||
| 10mg | 72.00 € | ||
| 25mg | 138.00 € | ||
| 50mg | 211.00 € | ||
| 100mg | 331.00 € | ||
| 500mg | 709.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
N-Oleoyl Valine Ammonium salt
N-Oleoyl Valine Ammonium salt is an N-acyl amide compound that is a TRPV3 antagonist and …
Formula:
C23H46N2O3
Purity:
99.92%
Color and Shape:
Solid
Molecular weight:
398.62
Ref: TM-T35921L
| 1mg | 197.00 € | ||
| 5mg | 488.00 € | ||
| 10mg | 685.00 € | ||
| 25mg | 1,069.00 € | ||
| 50mg | 1,475.00 € | ||
| 100mg | 1,888.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
JC-229
CAS:3026716-22-0
JC-229 is a potent and selective TbRPA1 inhibitor that can inhibit RPA1 in Trypanosoma brucei. …
Formula:
C20H14Cl4N2O3S
Purity:
97.14%
Color and Shape:
Solid
Molecular weight:
504.21
Ref: TM-T77645
| 10mg | 43.00 € | ||
| 25mg | 69.00 € | ||
| 50mg | 90.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
(S)-ABT 102
CAS:808756-70-9
N-[(1S)-1H-inden-1-yl]-N'-indazol-4-ylurea is a strong TRPV1 blocker with a 123 nM IC50 against capsaicin.
Formula:
C21H24N4O
Purity:
99.41% - 99.78%
Color and Shape:
Soild
Molecular weight:
348.44
Ref: TM-T29522L
| 1mg | 113.00 € | ||
| 2mg | 169.00 € | ||
| 5mg | 250.00 € | ||
| 10mg | 367.00 € | ||
| 25mg | 551.00 € | ||
| 50mg | 771.00 € | ||
| 100mg | 1,052.00 € | ||
| 500mg | 2,103.00 € | ||
| 1mL*10mM (DMSO) | 260.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
RN-1665
CAS:1803003-65-7
RN-1665 is a potent and selective TRPV4 receptor antagonist.
Formula:
C20H24F5N3O3S2
Purity:
100%
Color and Shape:
Soild
Molecular weight:
513.54
Ref: TM-T77723
| 1mg | 152.00 € | ||
| 5mg | 364.00 € | ||
| 10mg | 503.00 € | ||
| 25mg | 831.00 € | ||
| 50mg | 1,104.00 € | ||
| 100mg | 1,512.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
TRPM8 antagonist 3
CAS:2102179-29-1
TRPM8 antagonist 3 is a blocker of TRPM8 (IC50 = 11 nM).
Formula:
C13H12N2O4S
Purity:
99.25%
Color and Shape:
Solid
Molecular weight:
292.31
Ref: TM-T9709
| 1mg | 60.00 € | ||
| 5mg | 130.00 € | ||
| 10mg | 196.00 € | ||
| 25mg | 324.00 € | ||
| 50mg | 472.00 € | ||
| 100mg | 649.00 € | ||
| 200mg | 873.00 € | ||
| 1mL*10mM (DMSO) | 144.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
PF-04745637
CAS:1917294-46-2
PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1].
Formula:
C27H32ClF3N2O2
Purity:
97.91% - 99.3%
Color and Shape:
Solid
Molecular weight:
509
Ref: TM-T64337
| 1mg | 71.00 € | ||
| 5mg | 140.00 € | ||
| 10mg | 189.00 € | ||
| 25mg | 319.00 € | ||
| 50mg | 455.00 € | ||
| 100mg | 628.00 € | ||
| 200mg | 845.00 € | ||
| 1mL*10mM (DMSO) | 157.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
Vocacapsaicin hydrochloride
CAS:1931116-92-5
Vocacapsaicin hydrochloride (CA-008 hydrochloride) is a non-opioid TRPV1 agonist, a raw material for capsaicin, and …
Formula:
C26H42ClN3O4
Purity:
98.51% - 99.94%
Color and Shape:
Solid
Molecular weight:
496.08
Ref: TM-T39349
| 1mg | 375.00 € | ||
| 5mg | 915.00 € | ||
| 10mg | 1,217.00 € | ||
| 25mg | 1,839.00 € | ||
| 50mg | 2,471.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
Apcin A HCL
Apcin A HCL is an Apcin derivative. Apcin A HCL is an anaphase-promoting complex (APC) …
Formula:
C10H15Cl4N5O2
Purity:
99.30%
Color and Shape:
Solid
Molecular weight:
379.07
Ref: TM-T001
| 1mg | To inquire | ||
| 2mg | 63.00 € | ||
| 5mg | To inquire | ||
| 10mg | To inquire | ||
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 100mg | To inquire | ||
| 200mg | To inquire | ||
| 500mg | 2,792.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
TRPM4 inhibitor 8
CAS:1353979-43-7
TRPM4 inhibitor 8 is an inhibitor of Transient receptor potential melastatin 4(TRPM4) which contributes to …
Formula:
C11H17BrN2
Purity:
97%
Color and Shape:
Solid
Molecular weight:
257.17
Ref: TM-T9776
| 5mg | 46.00 € | ||
| 10mg | 64.00 € | ||
| 25mg | 94.00 € | ||
| 50mg | 176.00 € | ||
| 100mg | 276.00 € | ||
| 200mg | 415.00 € | ||
| 500mg | 681.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Friday 8 Nov 2024
ICILIN
CAS:36945-98-9
ICILIN (AG-3-5) is a synthetic TRPM8 ion channel super-agonist.
Formula:
C16H13N3O4
Purity:
97.61% - ≥95%
Color and Shape:
Light Yellow Solid
Molecular weight:
311.29
Ref: TM-T1814
| 5mg | 36.00 € | ||
| 10mg | 57.00 € | ||
| 25mg | 95.00 € | ||
| 50mg | 169.00 € | ||
| 100mg | 292.00 € | ||
| 1mL*10mM (DMSO) | 41.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
BCTC
CAS:393514-24-4
BCTC is a potent TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 …
Formula:
C20H25ClN4O
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
372.89
Ref: TM-T7102
| 5mg | 36.00 € | ||
| 10mg | 47.00 € | ||
| 25mg | 87.00 € | ||
| 50mg | 147.00 € | ||
| 100mg | 214.00 € | ||
| 200mg | 318.00 € | ||
| 1mL*10mM (DMSO) | 41.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
