Product Information
- 10-Hydroxy-1-decyne
- 2-Decyn-2-Ol
- 9-Decynyl alcohol
- Dec-9-yn-1-ol
9-Decyn-1-ol is an alkyl/ether-based PROTAC linker suitable for synthesizing PROTACs. It serves as a conjugation agent to combine GDC-0068 and Lenalidomide, resulting in the formation of INY-03-041. INY-03-041 is a potent and highly selective pan-Akt degrader that operates through the PROTAC mechanism. It effectively inhibits Akt1, Akt2, and Akt3 with IC50 values of 2.0 nM, 6.8 nM, and 3.5 nM, respectively[1].
Chemical properties
Technical inquiry about: TM-T17346 9-Decyn-1-ol
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