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PF-06273340
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PF-06273340

CAS: 1402438-74-7

Ref. TM-T19649

1mg
53.00 €
25mgTo inquire
50mgTo inquire
1ml*10 (DMSO)
278.00 €
Estimated delivery in United States, on Thursday 8 Aug 2024

Product Information

Name:
PF-06273340
Synonyms:
  • PF 6273340, PF 06273340, PF6273340, PF-6273340
Description:

PF-06273340 is an effective, Selective, and Peripherally Restricted Pan-Trk inhibitor (IC50: Trk-A = 6 nM; Trk-B = 4 nM; Trk-C = 3 nM). PF-06273340 has low metabolic turnover in HLM and hHep is a good substrate for efflux transporters P-gp (ER = 35.7) and BCRP (ER = 4.0) and has moderate passive permeability (RRCK Papp = 5.4 × 10 6 cm s 1).

Brand:
Targetmol
Long term storage:
Notes:

Chemical properties

Molecular weight:
479.92
Formula:
C23H22ClN7O3
Purity:
98.00%
Color/Form:
Solid
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

Technical inquiry about: TM-T19649 PF-06273340

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