Trk receptor
Trk receptor inhibitors target the Tropomyosin receptor kinases (Trk), a family of receptor tyrosine kinases that play a significant role in the development and function of the nervous system. Trk receptors are involved in neurotrophin signaling, which is essential for the survival, differentiation, and growth of neurons. Dysregulation of Trk signaling is associated with neurological disorders and certain cancers. At CymitQuimica, we offer Trk receptor inhibitors to support your research in neurobiology, oncology, and neurodegenerative diseases.
Found 70 products for "Trk receptor".
Filter by
Purity percentage
0
100
|
0
|
50
|
90
|
95
|
100
- Lower prices
- Higher prices
- Lower purities
- Higher purities
- Faster estimated delivery
N-Acetyl-5-hydroxytryptamine
CAS:N-Acetyl-5-hydroxytryptamine, or Normelatonin, is melatonin's precursor, made from serotonin, and activates TrkB receptor.Formula:C12H14N2O2Purity:98.31% - 99.91%Color and Shape:Yellow SolidMolecular weight:218.2518CE-245677
CAS:CE-245677 is a potent reversible inhibitor of Tie2 and TrkA/B kinases. With a cellular IC50s of 4.7 and 1 nM.Formula:C24H22Cl2N6O3Purity:98.99% - 99.23%Color and Shape:SolidMolecular weight:513.376Amitriptyline hydrochloride
CAS:Amitriptyline hydrochloride (Annoyltin) is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptiveFormula:C20H24ClNPurity:99.39% - 99.94%Color and Shape:SolidMolecular weight:313.864TrkA-IN-6
TrkA-IN-6 (compound R48) is a hydrazone-based, selective inhibitor of the tropomyosin receptor kinase A (TrkA). It exhibits greater cytotoxicity towards U87 GBM cells compared to Temozolomide, with an IC50 of 68.99 μM.Formula:C16H13N3O5Color and Shape:SolidMolecular weight:327.08552Protein kinase inhibitor 5 sulfate hydrate
Protein kinase inhibitor 5 sulfate hydrate, a potent TRK-A inhibitor, exhibits an IC50 of 1.8 nM and impairs cell viability [1].Formula:C29H35F2N7O6SPurity:98%Color and Shape:SolidMolecular weight:647.69Luvagrobart
CAS:Luvagrobart is a human monoclonal antibody targeting NGF that inhibits NGF binding to its receptor and is used in pain therapy research.Purity:95%Molecular weight:~150 kDaGNF-8625 monopyridin-N-piperazine hydrochloride
CAS:GNF-8625 monopyridin-N-piperazine hydrochloride is a protomyosin receptor kinase (TRK) inhibitor.Formula:C25H27ClFN7Purity:99.16%Color and Shape:SolidMolecular weight:479.98TRK-IN-31 hydrochloride
TRK-IN-31 hydrochloride is an orally active TRK inhibitor with an IC50 of 1.8 nM. It demonstrates excellent antiproliferative activity in Ba/F3-MPRIP-TRKAG667C cells and selectively inhibits TRK kinase activity. Additionally, TRK-IN-31 hydrochloride significantly suppresses tumor growth in a Ba/F3-MPRIP-TRKAG667C subcutaneous mouse model.Anti-Human NGF Antibody (5D767)
Anti-NGF Antibody (5D767) is a Rabbit IgG monoclonal antibody targeting Human NGF.Color and Shape:Odour LiquidAnti-Human NGF Antibody (8W871)
Anti-NGF Antibody (8W871) is a Rabbit IgG monoclonal antibody targeting Human NGF.PF-06737007
CAS:PF-06737007 is an effective inhibitor of pan-Trk in cell-based assays (IC50s: 7.7 nM, 15 nM, and 3.9 nM for TrkA, TrkB, and TrkC, respectively).Formula:C25H28F4N2O6Purity:98%Color and Shape:SolidMolecular weight:528.49Anti-Human NGF/bNGF Antibody
Anti-NGF/bNGF Antibody is a neutralizing mAb targeting β-NGF used to study chronic pain and inflammatory mechanisms by blocking NGF signaling.GBR-900
GBR-900 is an anti-TrkA mAb that inhibits pain signaling by blocking NGF binding, used for chronic pain with a better safety profile than anti-NGF antibodies.Purity:95%Molecular weight:145.90 kDa (Predicted)Anti-Human TrkB/NTRK2 Antibody
Anti-TrkB/NTRK2 Antibody is a potent monoclonal antibody targeting the TrkB/NTRK2 receptor. Anti-TrkB/NTRK2 Antibody demonstrates significant receptor engagement activity in vitro and facilitates the measurable protection of neuronal integrity while improving cognitive performance in various preclinical models of neurodegeneration.Color and Shape:Odour LiquidAnti-Human MUSK Antibody
Anti-MUSK Antibody serves as a functional therapeutic tool specifically designed to enable the precise detection and neutralization of the muscle-specific kinase which plays a pivotal role in the maintenance of the neuromuscular junction structural integrity during strictly monitored laboratory observation periods and molecular investigations to evaluate the pathological consequences of receptor tyrosine kinase inhibition in advanced neuroscience and immunology research models to facilitate the study of neuromuscular disorders.Purity:95%Molecular weight:143.84 kDa (Predicted)CH7057288
CAS:CH7057288 is an effective and selective TRK inhibitor with an IC50 value of 1.1 nM, 7.8 nM and 5.1 nM for TRKA, TRKB and TRKC, respectively.Formula:C32H31N3O5SPurity:99.92%Color and Shape:SolidMolecular weight:569.671Entrectinib
CAS:Entrectinib (RXDX-101) is an orally Trk, ROS1, and ALK inhibitor. Entrectinib exhibits antitumor activity. Cost-effective and quality-assured.Formula:C31H34F2N6O2Purity:98.03% - 99.67%Color and Shape:SolidMolecular weight:560.64LOXO-195
CAS:(6RS)-LOXO-195 (BAY 2731954) is a potent and selective Trk tyrosine kinase inhibitor.Formula:C20H21FN6OPurity:99.54%Color and Shape:SolidMolecular weight:380.4187Cyclotraxin B acetate
Cyclotraxin B acetate is an antagonist of TrkB receptors; inhibits BDNF-induced TrkB activity (IC50 = 0.30 nM).Formula:C50H77N13O19S3Purity:99.73%Color and Shape:SolidMolecular weight:1260.42Altiratinib
CAS:Altiratinib (DCC-2701)(DCC-2701) is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling,Formula:C26H21F3N4O4Purity:99.67% - 99.75%Color and Shape:SolidMolecular weight:510.4645
