FOXJ1 agonist 1
Ref. TM-T200312
Product Information
Name:FOXJ1 agonist 1
Brand:Targetmol
Description:FOXJ1 agonist 1 (compound 16c), an orally effective small molecule, effectively enhances FOXJ1 expression and acts on multiciliated cells (MCC) in the mammalian airway system to prevent chronic obstructive pulmonary disease (COPD). Foxj1-IN-1 induces motile cilia production in the respiratory system of both zebrafish and mammals and inhibits elastase-induced COPD in mouse models. Additionally, Foxj1-IN-1 demonstrates good liver microsomal stability and favorable in vivo pharmacokinetic (PK) curves and area under the curve (AUC). It exhibits negligible inhibition of CYP and hERG and lacks significant cytotoxicity.
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Chemical properties
Molecular weight:433.5
Formula:C24H27N5O3
Color/Form:Solid
Technical inquiry about: FOXJ1 agonist 1
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