Product Information
GSK_WRN4, a WRN helicase inhibitor (pIC50=7.6), demonstrates anticancer activity by selectively inhibiting the growth of MSI tumor cells both in vitro and in vivo. It induces DNA double-strand breaks, specifically at amplified TA repeats and DNA damage sites.
Chemical properties
Technical inquiry about: TM-T200332 GSK_WRN4
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