Product Information
Name:XJTU-L453
Brand:Targetmol
Description:XJTU-L453, a PI3Kα inhibitor, exhibits an IC50 of 0.4 nM. It inhibits the proliferation of breast cancer cell lines T47D and MCF7, with IC50 values of 0.2 μM and 0.5 μM respectively. Additionally, XJTU-L453 disrupts the PI3K pathway, leading to cell cycle arrest and cell apoptosis (apoptosis). It also demonstrates antitumor activity in MCF7 xenograft mice.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:390.44
Formula:C22H22N4O3
Color/Form:Solid
Technical inquiry about: XJTU-L453
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