


COX-2-IN-48
Ref. TM-T200441
10mg | To inquire | ||
50mg | To inquire |
Product Information
COX-2-IN-48 (5-25) serves as an inhibitor of COX-2, exhibiting an IC50 of 51.7 nM against human COX-2. It displays anti-inflammatory and analgesic effects in various rodent models through inhibition of the NF-κB pathway. COX-2-IN-48 (5-25) inhibits the degradation of IκB, phosphorylation and nuclear translocation of NF-κB p65, and the expression of COX-2 and iNOS.
Chemical properties
Technical inquiry about: TM-T200441 COX-2-IN-48
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