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ZLY06

CAS:

Ref. TM-T200490

ZLY06
Targetmol

Product Information

Name:ZLY06
Brand:Targetmol
Description:ZLY06 is a dual agonist of peroxisome proliferator-activated receptors (PPAR) δ and γ with oral activity (PPAR δ: EC50=341 nM; PPARγ: EC50=237 nM). It mediates the upregulation of CD36 and induces hepatic lipid accumulation by inhibiting the phosphorylation of AKT1. Moreover, ZLY06 significantly improves glucose and lipid metabolism without increasing body weight, primarily by enhancing the β-oxidation of fatty acids and reducing hepatic lipid synthesis, thereby alleviating fatty liver disease.
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Chemical properties

Molecular weight:422.47
Formula:C25H26O6
Color/Form:Solid

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