HDAC-IN-79
Ref. TM-T200527
10mg
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50mg
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Product Information
Name:HDAC-IN-79
Brand:Targetmol
Description:HDAC-IN-79 (compound 4) is an orally active dual inhibitor of xanthine oxidase and HDAC, exhibiting potent anti-hyperuricemia and antitumor activities in vivo (Xanthine oxidase: IC50=6.6 nM; HDAC1: IC50=134 nM; HDAC2: IC50=284 nM; HDAC3: IC50=173 nM; HDAC6: IC50=1.32 nM). Among leukemia cells, it is most effective in inhibiting the growth of HL60 cells (IC50=0.706 μM) and induces both apoptosis and autophagy. HDAC-IN-79 also modulates the expression levels of biomarkers associated with intracellular HDAC inhibition.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Color/Form:Odour Solid
Technical inquiry about: HDAC-IN-79
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