Product Information
D228 is an orally-administered anti-inflammatory compound effective against inflammatory bowel disease (IBD). It reduces ConA-induced T lymphocyte proliferation (IC50: 42.85 μM) and LPS-induced B lymphocyte proliferation (IC50: 3.15 μM). D228 alleviates inflammation in IBD models induced by DSS by downregulating the MyD88/TRAF6/p38 signaling pathway.
Chemical properties
Technical inquiry about: TM-T200551 D228
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