Product Information
Name:ALK5-IN-82
Brand:Targetmol
Description:ALK5-IN-82 is a potent and selective inhibitor of activin receptor-like kinase 5 (ALK5), demonstrating an IC50 value of 9.1 nM. This compound effectively suppresses the expression of α-smooth muscle actin (α-SMA), collagen I, and the proteinases tissue inhibitor of metalloproteinase 1 (TIMP-1) and matrix metalloproteinase 13 (MMP-13) in human umbilical vein endothelial cells induced by transforming growth factor-β. ALK5-IN-82 shows potential for use in research related to cardiac fibrosis.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:429.50
Formula:C22H19N7OS
Color/Form:Solid
Technical inquiry about: ALK5-IN-82
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