Product Information
Name:GDCNF-11
Brand:Targetmol
Description:GDCNF-11, an HSP90-based HIM-PROTACGPX4 degrader, facilitates the ubiquitination and degradation of GPX4 through the HSP90 chaperone complex. This reduction in endogenous GPX4 induces ferroptosis in HT-1080 cells, with a DC50 value of 0.08 μM.
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Chemical properties
Molecular weight:994.99
Formula:C48H53Cl2N13O5S
Color/Form:Solid
Technical inquiry about: GDCNF-11
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