CV-4-26
Ref. TM-T200708
10mg | To inquire | ||
50mg | To inquire |
Product Information
CV-4-26 (Compound 22) acts as a covalent inhibitor of TEAD. By inhibiting YAP/TEAD-driven transcription, it diminishes the expression of CTGF and CYR61. Furthermore, CV-4-26 impedes colony formation in Huh7 and HepG2 cells, inducing cell cycle arrest and apoptosis (apoptosis). This compound demonstrates anti-tumoral activity against hepatocellular carcinoma (HCC) and hepatoblastoma (HB).
Chemical properties
Technical inquiry about: TM-T200708 CV-4-26
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