Antiproliferative agent-59
Ref. TM-T201186
Product Information
Name:Antiproliferative agent-59
Brand:Targetmol
Description:Antiproliferative agent-59 (Compound 14u) acts as an inhibitor of tubulin polymerization. Demonstrating anticancer activity in Huh7, SGC-7901, and MCF-7 cell lines, this compound achieves IC50 values of 0.03, 0.18, and 0.13 μM, respectively. Additionally, it arrests the cell cycle at the G2/M phase and induces apoptosis in Huh7 cells. In a xenograft mouse model utilizing Huh7 cells, Antiproliferative agent-59 exhibits antitumor effects against hepatocellular carcinoma without significant toxicity.
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Chemical properties
Molecular weight:410.46
Formula:C26H22N2O3
Color/Form:Solid
Technical inquiry about: Antiproliferative agent-59
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