YJ9069
Ref. TM-T201264
10mg
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50mg
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Product Information
Name:YJ9069
Brand:Targetmol
Description:YJ9069 is a selective CDK12/CDK13P ROTAC degrader with an IC50 of 22.22 nM in VCaP cells. Rapid degradation of CDK12/13 by this compound triggers transcription elongation defects dependent on gene length, leading to DNA damage and cell cycle arrest. YJ9069 effectively inhibits the proliferation of prostate cancer cell subpopulations and significantly suppresses prostate tumor growth in vivo.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:850.92
Formula:C46H46N10O7
Color/Form:Solid
Technical inquiry about: YJ9069
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