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ART899

CAS:

Ref. TM-T201365

ART899
Targetmol

Product Information

Name:ART899
Brand:Targetmol
Description:ART899, a derivative of ART558, is a potent and specific conformational inhibitor of DNA polymerase θ (Polθ). It specifically inhibits the MMEJ activity of Polθ with an IC50 of 180 nM. Additionally, ART899 selectively enhances the radiosensitivity of tumor cells and possesses a strong independent antitumor effect on cancer cells.
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Chemical properties

Molecular weight:464.81
Formula:C19H16ClF4N3O4
Color/Form:Solid

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