
PfCLK3-IN-1
Ref. TM-T201861
10mg | To inquire | ||
50mg | To inquire |
Product Information
PfCLK3-IN-1 (Compound 4) serves as a covalent inhibitor of the malaria parasite CLK3 (Pf CLK3) under alkaline conditions, with a pEC50 of 7.1. It inhibits the maturation of gametocytes during the sexual stage of the parasite, thereby hindering transmission. Additionally, PfCLK3-IN-1 effectively suppresses the Dd2-B2 clone of the malaria parasite, exhibiting an IC50 of 239.5 nM.
Chemical properties
Technical inquiry about: TM-T201861 PfCLK3-IN-1
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