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LZ-007

CAS:

Ref. TM-T203062

LZ-007
Targetmol

Product Information

Name:LZ-007
Brand:Targetmol
Description:LZ-007 is an agonist of the Farnesoid X receptor (FXR), with an EC50 of 51 nM as determined by TR-FRET assay, and an EC50 of 76 nM in HepG2 cells. It exhibits favorable pharmacokinetic properties in SD rats and can improve metabolic dysfunction-associated steatohepatitis induced by high-fat diets and CCl4 in mice.
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Chemical properties

Molecular weight:518.53
Formula:C27H29F3N2O5
Color/Form:Solid

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