PROTAC KSP-IN-1
Ref. TM-T203186
10mg
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50mg
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Product Information
Name:PROTAC KSP-IN-1
Brand:Targetmol
Description:PROTACKSP-IN-1 (Compound 21) is a spindle protein (KSP) degrader as a PROTAC, effectively degrading KSP in HCT-116 cells with a DC50 value of 114.8 nM. It inhibits the proliferation of HCT-116 with an IC50 of 10 nM, causes G2/M phase cell cycle arrest, and induces apoptosis in HCT-116. Additionally, PROTACKSP-IN-1 demonstrates antitumor activity in mouse models.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:858.01
Formula:C48H51N5O8S
Color/Form:Solid
Technical inquiry about: PROTAC KSP-IN-1
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