Product Information
Name:1,2,3,6,7,8-Hexachlorodibenzofuran
Synonyms:
- 1,2,3,6,7,8-HxCDF
Brand:Targetmol
Description:1,2,3,6,7,8-Hexachlorodibenzofuran (1,2,3,6,7,8-HxCDF) is a type of polychlorinated dibenzofuran (PCDF). It promotes the expression of aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin-O-deethylase (EROD) genes in H-4-II-E rat hepatoma cells with EC50 values of 1.47 and 1.24 nM, respectively. 1,2,3,6,7,8-HxCDF also reduces rat body weight, causes thymic atrophy, and induces the expression of cytochrome P450 (CYP) subtype CYP1A1 and 4-chlorobiphenyl hydroxylase genes with EC50 values of 3.2, 0.9, 0.35, and 0.21 µmol/kg.
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Chemical properties
Molecular weight:374.86
Formula:C12H2Cl6O
Color/Form:Solid
Technical inquiry about: 1,2,3,6,7,8-Hexachlorodibenzofuran
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